PREVALENCE OF MICROALBUMINURIA AND ASSOCIATED RISK FACTORS IN YOUNG INDIAN TYPE 2 DIABETES SUBJECTS ATTENDING A TERTIARY DIABETES CARE INSTITUTE

Dr. R. Anil Kumar*

ABSTRACT

Aims and Objectives: To find out the prevalence of microalbuminuria in young Indian type 2 diabetes subjects with age of onset of diabetes less than 35 years. Material and Methods: Type 2 diabetic subjects 373 in number were selected from patients with age of onset of diabetes less than 35 years attending Karnataka institute of endocrinology and research over a period of 2 years. Results: Age of diabetes subjects range from 20 to 50 years with age of onset of diabetes less than 35 years in all the participants. 71.8% of diabetes subjects were males. 54.7% of subjects had BMI 18.5 to 25 and 37.8% of subjects had BMI 25 to 30. Waist circumference was 80 to 90 cms in 54.7% and 90 to 100 cm in 25.2% of subjects. Fasting plasma glucose was more than 126 mg/dl in 77.2% of the subjects. Postprandial plasma glucose of 72.9% of subjects was more than 200 mg/dl.The target HBA1c of <7% was achieved only in 18.4% of young diabetes subjects. The glycemic control of young diabetics was not good in many studies. In this study the HBA1c was more than 9% in 55.5% of the diabetes subjects. Microalbuminuria was present in 23.3% and macroalbuminuria in 4.6% of young diabetes subjects. Systolic BP, HBA1c, BMI and duration of diabetes are correlated with microalbuminuria. Conclusions: Microalbuminuria was present in 23.6% of young diabetes subjects with age of onset of diabetes less than 35 years. Only 18.4% of the patients HBA1C was less than 7%. The glycemic control of young diabetics was not good in many studies. In this study the HBA1c was more than 9% in 55.5% of the diabetes subjects. So it is essential to achieve Glycemic targets and blood pressure targets in young diabetes subjects to retard progression from microalbuminuria to macroalbminuria and in few patients we can revert to normoalbuminuria.

Keywords: Type 2 diabetes, Microalbuminuria, Nephropathy.