COMPARATIVE STUDY OF EFFECT OF OLMESARTAN AND CILNIDIPINE ON MICRO ALBUMINURIA LEVELS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Rajesh Kadam, Bhakti N. Chandekar*, Snehal Chavan and Deepak S. Bhosle

ABSTRACT

The International Diabetic Federation estimated that in 2015, the prevalence of diabetes from ages 20 to 79 years was 8.8%.[1] By the year 2030, it is estimated that India will be having 79.4 million diabetic patients and 439 million adults will be affected in the world (corresponding to 7.8% of the world's adult population).[2] Chronic long term microvascular and macrovascular tissue complications are one of the most important clinical features associated with diabetes. The major causative factor in initiating organ damage is duration and severity of hyperglycemia.[3] For small blood vessels in organs like kidney, eyes and nerves to get affected, it almost takes 15 years. The kidney is the most important target of microvascular damage in both type 1 (T1DM) and type 2 diabetes mellitus (T2DM).[4,5] It has been observed that almost 20 to 40% of diabetic patients are at the risk of developing chronic kidney disease (CKD).[5]

Keywords: term microvascular and macrovascular.