A CLINICOEPIDEMOLOGICAL STUDY OF ACUTE KIDNEY INJURY AMONG PATIENTS ADMITTED WITH SHORT DURATION FEVER

Dr. Debajyoti Majumdar, *Dr. Arindam Naskar, Dr. Manab Kumar Ghosh, Dr. Sudeshna Mallik and Prof. (Dr.) Bibhuti Saha

ABSTRACT

Acute kidney injury associated with fever in tropics is predominantly community acquired and affects young, previously healthy persons. In this prospective study from a tertiary care centre in Eastern India, the common acute febrile illnesses among hospitalized patients included dengue, malaria, typhoid, lower respiratory tract infections, scrub typhus, urinary tract infection, leptospirosis, mixed infections and others. Overall incidence of AKI was 18.54%. AKI was present in 100%in patient with leptospirosis, 50% in LRTI, 12.8% in Dengue and 11.8% in P. Vivax. Despite the use of a standard battery of tests for acute febrile illness, the aetiology of fever could not be ascertained in 6.7% of the patients, who had 20% of AKI without any mortality. The study showed significantly higher incidence of AKI in elderly, male, known diabetic and hypertensive patients. It is now possible to identify patients at an early stage of AKI using KDIGO criteria and effective therapeutic or preventive measures that can contain and prevent AKI reducing morbidity and mortality thus saving money and lives.

Keywords: 1. AKI- Acute Kidney Injury 2. KDIGO- Kidney Disease: Improving Global Outcomes 3. Short duration fever.