EVALUATION OF PRIMARY CNS TUMORS IN A SAMPLE OF IRAQI PATIENTS CLINICOPATHOLGICAL STUDY

Prof. Alaa Ghani Hussein MBChB, FICMS and Maab M. Hameed MBChB.*

ABSTRACT

Introduction: Primary brain tumors include tumors that originate from the tissues of the brain or the brain's immediate surroundings. Primary tumors are categorized as glial (composed of glial cells) or non-glial (developed on or in the structures of the brain, including nerves, blood vessels and glands) and benign or malignant. Glioma and meningioma are the most commone types. Aim of study: To assess the frequency of different types of primary CNS (central nervous system) tumors in Bagdad medical city and to assess the relation with age, gender and clinical symptoms. Subject and method: A retrospective analysis of 60 randomly selected patients with primary brain tumor collected from Teaching Laboratories of Baghdad Medical City from January 2019 to January 2020. The data collection will include:- Demographic analysis (age, residency and gender). Clinical presentation (include persistent headache, seizures, nausea, vomiting, neurocognitive symptoms, and personality changes….ect). Post-operative histopathological diagnosis. Data will be collected from patient archived pathological report. Then statistical analysis will be done to assess frequency of different types of primary brain tumors and their clinicopathologicl parameters. Results: During this study the total number of collected cases is 60,there were 40 (66.66%) diagnosed as glioma and meningioma, headache was the most common clinical presentation 18 (30%), Male predominance, the age of patient range from 0-74 years ,the highest primary CNS tumor (48.33%) was found in patients between 15-49 years old. Conclusion: In this study I found that meningioma and glioma (astrocytoma) are the most common type of primary CNS tumor. Headache is the most clinical presentation, male predominance. the highest primary CNS tumor (48.33%) was found in patients between 15-49 years old. because our country considered a high reproductive country and low average age in general.

Keywords: Primary CNS tumors, meningioma, astrocytoma, headache, Gender distribution in primary CNS tumor.