ACUTE TRANSFORMATION FROM FANCONI ANEMIA (FA) TO ACUTE MYELOID LEUKEMIA (AML) IN CHILD: CASE REPORT

S. Hasnane*, A. Jarmoumi, S. Laajouri, H. Bencharef, A. Quessar and B. Oukkache

ABSTRACT

Fanconi Anemia (FA) is a rare autosomal recessive disease that is part of the chromosomal instability syndromes. In addition to their risk of hematologic malignancies, people with FA have a too high risk of developing a solid tumor. In this article, we report the case of a young patient with fanconi anemia who developed a malignant transformation into acute myeloid leukemia after one year from his diagnosis of fanconi anemia and during his allograft programming.

Keywords: Fanconi anemia, child, AML, transformation.