PHTOCHEMICAL & PHARMACOLOGICAL HEPATOPROTECTIVE SCREENING OF LUFFA ACUTANGULA

Parmeena Khatoon, Dr. Shamim Ahmad, Dr. Nasirudin Ahmad Farooqui* and Mohd Salman

ABSTRACT

The Present investigation entitled “Phytochemical & Pharmacological Hepatoprotective screening of Luffa acutangula” on Experimental Animals has been carried out and presented in the thesis. The aim of present study to evaluated heptoprotective activity of Luffa acutangula. Hepatotoxicity in rats was induced by carban tetrachloride (1ml/kg). Alcoholic extract of Luffa acutangula showed good hepatoprotective activity. The present investigation is concerned with the widely distributed indigenous plants Luffa acutangula from the survey of literature of this plant, it is observed that this plant is well known, in order to do a systematic study. We have gone in for a treatment of a set of ailments by diverse plants species from different family. Luffa acutangula belongs to the family of Cucurbitaceae was reported to possess Hepatoprotective and. Mature fruits are used as natural cleaning sponges. Its fruit slightly resembles a cucumber or zucchini with ridges. It ranges from central and eastern Asia to southeastern Asia. Luffa acutangula was observed to be good source of fiber (20.6 %) and minerals (7.7 %). The estimated world market for plant and plant derived drugs which would cross more than 2000 billion during 2015 it was understood that a major percentage of world population relies mainly on plants and plant extracts for health care.

Keywords: Luffa acutangula, Hepatoprotective, Antioxidant activity.