INVASIVE FRONTAL BONE SINUS ASPERGILLOSIS – A CASE REPORT

Chatterjee R., Chakraborty A., Sarkar K.*, Pramanik N. and Ghosh T.

ABSTRACT

Aspergillus species are ubiquitous fungi present in environment with inhalation of spores(conidia) being a common event. However, inhalation of the spores causing fungal sinus infection with invasion of adjacent bony structures or disseminated invasive infection is a rare entity, seen only in immune suppressed individuals. Here, we report a case of a 24 years male, known case of Generalised tonic-clonic seizure on regular anti-epileptics, otherwise immunocompetent without any comorbidity who presented to us with recurrent swelling with discharge over left frontal region of forehead – at site of previously operated myofibroblastic tumour. Biopsy specimen was taken after surgical debridement of the swelling showed presence of fungal hyphae suggestive of Aspergillosis. The patient was treated with Amphotericin B followed by long term voriconazole therapy.

Keywords: Aspergillosis, frontal sinus, fungal hyphae, voriconazole.