A COMPARATIVE STUDY ON ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY WITH AND WITHOUT ANTIMICROBIAL PROPHYLAXIS IN VIEW OF POST OPERATIVE SURGICAL SITE INFECTIONS

Dr. Hitesh Kumar, Dr. A. K Gupta, Dr. Shivani Sharma and Dr. Dharam Dev*

ABSTRACT

Background: Laparoscopic cholecystectomy has become the gold standard treatment for gallstone disease. Aim of the study is to compare the laparoscopic cholecystectomy with and without antibiotic prophylaxis in term of post operative surgical site infection. Method : This prospective study was carried out in the department of General Surgery Indira Gandhi Medical College Shimla (H.P) on patients admitted with diagnosis of cholelithiasis, over a period of 1 year from 1st August, 2018 to 31st July, 2019.total of 100 patients were included in the study,and were randomly divided into two groups. Group A was control group in which antibiotic was given and group B was case group in which no antibiotic was given. Result: In the present study wound infection occurred in 2 out of 50 patients (4%) in case group and 1 out of 50 patients (2%) in control group, all of them had superficial SSI. The difference was statistically not significant with P value of 1. Both the groups were comparable in terms of surgical site infection. Conclusion: As elective LC is a clean surgery,therefore In low-risk patients antibiotic prophylaxis does not seem to affect the incidence of postoperative infective complications.It is justified only in high-risk patients. In all other patients, eliminating the unnecessary use of prophylactic antibiotics would result in cost reductution,decreases microbial resistance and adverse drug reactions.

Keywords: Prophylactic antibiotics, Laparoscopic Cholecystectomy.