SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW

Kiran Kamthe*, Darshan Kalugade*, Manoj Jograna and Ashok Bhosale

ABSTRACT

Self-emulsifying drug delivery systems (SEDDS), which are isotropic mixtures of oils, surfactants, solvents and co-solvents/surfactants, may be used for the design of formulations a good way to improve the oral absorption of enormously lipophilic drug compounds. these structures shape first-rate emulsions (or micro-emulsions) in gastro-intestinal tract (GIT) with mild agitation furnished through gastric mobility. Many parameters like surfactant awareness, oil/surfactant ratio, polarity of the emulsion, droplet size and rate plays a critical position in oral absorption of drug from SEEDS. This formulation superior bioavailability due to growth the solubility of drug and minimizes the gastric infection. The reality that almost 40% of the new drug compounds are hydrophobic in nature means that research with SEDDS will continue, and

Keywords: Self-emulsifying drug delivery systems, isotropic, emulsions, bioavailability.