A CASE REPORT OF NEONATAL MELIOIDOSIS FROM A TERTIARY CARE HOSPITAL, BANGLADESH.

*Dr. Abu Naser Ibne Sattar and Dr. Sanjida Khondakar Setu

ABSTRACT

Gram-negative environmental bacterium Burkholderia pseudomallei is the aetiological agent of melioidosis. About 89,000 deaths per year worldwide occurs due to this life-threatening infection. Manifestations of melioidosis can range from acute septicaemia to chronic infection. Due to its facultative intracellular survival and virulence factors, B. pseudomallei can manipulate the host's immune responses and signalling pathway to escape immune surveillance. Difficulties in clinical recognition and laboratory diagnosis of melioidosis causes delay in proper antimicrobial therapy. Which often lead to poor outcomes and mortality. For early confirmation of the diseases, better diagnostic tests are needed, which would enable better therapeutic efficacy and survival.

Keywords: Burkholderia pseudomallei, neonatal melioidosis, sepsis, apgar score.