A STUDY OF CLINICAL PROFILE OF COVID-19 IN A TERTIARY HEALTH CARE CENTRE

*Nandish Kumar R, Vasantha Kamath and M. J. Jacob

ABSTRACT

Background: SARS-CoV-2 virus rapidly spread from Wuhan to rest of the world leading to a global pandemic. COVID-19 can have diverse range of clinical presentations. In our study we review the clinical profile, laboratory parameters, comorbidities, duration of hospital stay, treatment and fatality of COVID-19 patients. Methodology: A total of 1754 patients with confirmed COVID-19 infection were admitted at a rural tertiary care centre, Karnataka, India. It is a prospective observational study done for a period of six months from July 2020 to December 2020. Clinical data including demographic data, symptomatology, comorbidities, laboratory parameters, treatment and complications were recorded. Results: Out of 1754 COVID-19 patients, males were affected more than females. Most of them were middle-aged (40.5%). 69.6% had pulmonary manifestations. 20.5% had extra pulmonary manifestations in the form of neurological, gastrointestinal, cardiovascular, cutaneous symptoms. 60.9% patients had pre-existing comorbidities. Overall fatality was 4.27%. Conclusion: In our study we concluded that COVID-19 can have both pulmonary and extra-pulmonary manifestations and fatality correlated with the severity of COVID-19 infection.

Keywords: COVID-19, Pulmonary, Extrapulmonary, inflammatory markers, ARDS.