ANTI-OXIDANT AND HEPATOPROTECTIVE ACTIVITY OF FRUIT EXTRACTS OF LAGENARIA SICERARIA AND LUFFA ACUTANGULA IN RIFAMPICIN INDUCED HEPATOTOXICITY IN RATS

Safora Sanober* and Dr. Shaik Mohammed Khasim

ABSTRACT

Liver is mindful for numerous physiological works out in spite of the reality that it may uncover itself to different dangerous drugs , chemicals and drugs due to the morals of the closeness to additional sum of protein and thus. In our understanding around hepatotoxicity, restorative drugs have been utilized to cause hepatitis hurt, as they are utilized for helpful purposes by human. All plants take action against oxidative Rifampicin push in rats through the diminishment of serum AST, serum ALT in liver oxidative push markers. The effects of antioxidant plants on both plants (lagenaria siceraria and luffa acutangula) are hot with antioxidant measurements. Rifampicin has increased oxidative stretch in the oxidative rats in the superoxide dismutase of the liver tissue.

Keywords: Rifampicin, antioxidant, lagenaria siceraria and luffa acutangula.