COMPARATIVE STUDIES AND ANTIMICROBIAL EMPIRE OF TWO MEDICINAL PLANTS FROM INDIA AGAINST CLINICAL ISOLATES OF STREPTOCOCCUS PNEUMONIAE

R. Kadhar Nivas*, Dr. M. Boominathan

ABSTRACT

To examine the in vitro antibacterial activity of the ethanol extract of fresh leaves of Allium cepa and Ficus bengalensis and to determine and quantify the phenol compounds of the investigated plant parts. This study was drifting out at the MP Institutions, Bhrathidasan University, Thanjavur, Tamilnadu, India from Sep 2014 to Oct 2014. Clinical strains of Streptococcus Pneumoniae and two ethanol extracts of two plant species were used for the antimicrobial study. Thirty grams of each sample was ground, filtrated, and each filtrate mixed with 100 ml ethanol and placed in a shaker for 48 hours. The ethanol was evaporated from the sample, weighed, and subjected to an antibacterial activity test using the agar diffusion method. The high- performance liquid chromatography was used to identify and quantify the phenols extracts of investigated samples. Ethanol extract of the investigated plant parts showed antibacterial activities against different pathogenic bacteria. Leaf extracts of Allium cepa showed the highest antibacterial activity, followed by the leaves of Ficus bengalensis. The amount of main phenols detected in Allium cepa higher than Ficus bengalensis. The ethanol extract of the tested plants could be considered as an alternative source of new antibacterial drugs.

Keywords: HPLC, Antimicrobial Empire, Streptococcus Pneumoniae, Medicinal Plants.