ORAL FAST DISINTEGRATING TABLET: AN OVERVIEW

*Bhavana A. G., Deekshitha A., Ranjith Gowda T. N. Sindhu A. C.

ABSTRACT

In the present scientific scenario the drug delivery technology has become highly competitive and rapidly evolving with ever increasing demand. Fast dissolving tablet (FDT) is one such type of an innovative and unique drug delivery system which is swiftly gaining much attention in the research field of rapid dissolving technology. Most of the drug products available in the market are for oral drug administration.[1] Oral route is preferred due to easy of administration, versatility, patient compliance and accurate dosing. However, oral administration is not suitable for people with dysphasia, a condition that results in a difficulty in swallowing. Also, for many geriatric paediatric patients, oral administration might not be a preferred route.[2] In this regards, oral disintegrating tablets (ODT) provide a useful alternative. When ODT comes in contact with saliva, this tablets disintegrate instantaneously (within 30 sec) resulting in the release of drug. Furthermore, since it under goes pre-gastric absorption, it bypasses first pass metabolism, which can be beneficial for drugs with significant hepatic metabolism.

Keywords: Oral disintegrating tablets, Dysphasia, Swallowing problems, Orodispersible tablets, Oral films.