GREEN SYNTHESIS OF SILVER NANOPARTICLES FROM THE AQUEOUS LEAF EXTRACT OF CASSIA ALATA AND ITS ANTI-INFLAMMATORY, ANTI-DIABETIC & CHARACTERIZATION STUDIES

Sidharth K.* and Dr. K. Narayanasamy

ABSTRACT

Nano science is an inspiring and influential discipline of science which has numerous novel and cost effective yields and applications. The main challenge in the development of catalytic NPs is to prepare nanomaterial’s that are highly active, selective, stable, robust, and inexpensive. There has been a growing need to replace the chemical synthetic procedures with clean, nontoxic, and environmentally acceptable green chemistry methods. Water soluble plant metabolites and co- enzymes present in plant extracts can be used to reduce metal ions to nanoparticles in a single-step green synthesis process. Among the metal nanoparticles, SNPs are considered to be of great importance because of their properties such as antiviral, antibacterial, antifungal, electrical conductivity, chemical stability and catalytic activity. Silver nanoparticles are nanoparticles of silver, i.e. silver particles of between 1 nm and 100 nm in size. Cassia alata (also known as Senna alata) is a shrub belonging to the fabaceae family, found in tropical areas. In the present scenario deals with the exploration and development of cheaper, effective plant based silver Nano particle with better bio active potential and least side effects. In this study involves the synthesis of AgNPs by an aqueous leaf extract of Cassia alata. The biologically synthesized silver nanoparticles showed effective anti- inflammatory, anti- diabetic activities.

Keywords: Cassia alata, green synthesis, AgNPs, characterization studies,anti-diabetic activity, anti-inflammatory activity.