A REVIEW ON FAST DISSOLVING FILMS FOR ORAL DELIVERY OF DRUGS

Km. Roshani, *Mangla Nand Singh, Dr. P. D. Panda, Jai Narayan Mishra and Reena Singh

ABSTRACT

The oral route is most popular route for the administration of therapeutic agents because of the low cost of therapy and ease of administration lead to high levels of patient compliance. These formulations are suitable for cold, allergic rhinitis, asthma attacks, CNS disorders where rapid onset of action is required for faster relief. The most popular oral solid dosage forms are tablets and capsules. Some companies introduced more robust forms of fast-dissolving drug delivery the film is placed on the top or the floor of the tongue. When put on the tongue, this film dissolves instantaneously, releasing the drug which dissolves in the saliva. Some drugs are absorbed from the mouth, pharynx and esophagus as the saliva passes down into the stomach. It leads to enhancing drug bioavailability, No risk of chocking, Provide good mouth feel. Fast dissolving drug delivery system bypasses problems associated with difficulty in swallowing tablets/capsules etc. This review article emphasizes on the advancement in the oral dosage forms, application, formulation consideration, method of preparation, evaluation, marketed products and patented technologies of oral fast dissolving films.

Keywords: Fast dissolving film, Onset of action, Bioavailability, Patients compliance.