EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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 ISSN 2394-3211

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Abstract

ROLE OF ISCHEMIA REVERSAL PROGRAM TO REDUCE MYOCARDIAL ISCHEMIA STUDIED WITH CARDIAC STRESS TESTING: AN OBSERVATIONAL STUDY

Rohit Sane, Pramod Manohar, Rahul Mandole*, Gurudatta Amin and Pravin Ghadigaokar

ABSTRACT

Background: Heart problems are considered a global epidemic, with cardiovascular disease being spread all over the world. Ischemia Reversal Program (IRP) is a form of Ayurvedic therapy which combines use of panchkarma and allied therapy in the management of IHD. Aim and objectives: The present study was planned to study the effectiveness of IRP therapy in patients of myocardial ischemia attending Madhavbaug clinics in Vidarbha region, Maharashtra. Materials and methods: This was a retrospective study conducted from June 2019 to December 2019, wherein we identified the data of patients suffering from IHD (positive for inducible ischemia from stress test) of either gender or any age, and who had attended the out-patient departments (OPDs) at Vidarbha region, Maharashtra, India. The data of patients who had been administered IRP with minimum 7 sittings over a span of 12 weeks were considered for the study. Results: In the present study, medical records of 50 patients of IHD were analyzed. At the end of IRP therapy there was statistically significant reduction in weight, BMI, SBP, and DBP. VO2 peak was improved at the end of therapy i.e. 26.51±5.93 mL/kg/min as compared to baseline i.e. 15.62±5.36 mL/kg/min and the difference was highly statistically significant (p<0.001). DTS improved from -2.93±5.88 at baseline to 3.21±6.03at week 12 of IRP therapy and the difference was highly statistically significant (p<0.0001). Conclusion: Findings of present study suggest that IRP can serve as effective therapeutic option for the management of myocardial ischemia.

Keywords: Ischemic Heart Disease, Ischemia Reversal Program, Ayurveda, Panchkarma, VO2 peak, Dukes Treadmill score.


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