THE EFFECT OF LAPAROSCOPIC AND OPEN SURGERY ON TRAUMATIC STRESS AND PROGNOSIS IN PATIENTS WITH COLON CANCER

Mohamed Said Jalloh, Baral Shantanu, Mubeen Hussein Arawker, Jun Ren, Dong Tang, Liuhua Wang and Daorong Wang*

ABSTRACT

Aim: to analyze the effects of laparoscopic surgery and open surgery on traumatic stress and prognosis in patients with colon tumor. Methods: 96 patients with colorectal tumors treated in the hospital from August 2012 to March 2015 were selected for study. They were randomly divided into minimally invasive group (laparoscopic surgery) and open group (open surgery). The operation related indexes, trauma stress indexes, complications and prognosis related indexes of the two groups were compared. Results: The intraoperative blood output of minimally invasive group was lower than that of open group, and the incision length was shorter than that of open group, The recovery and exhaust time of anus was earlier than that of laparotomy group (P < 0.05). There was no significant difference in operation time, lymph node clearance and hospitalization time between the two groups (P > 0.05). The levels of aldosterone, cortisol and upper gland surface in minimally invasive group were lower than those in laparotomy group at 1D, 3D and 5D after operation (P < 0.05) There was no significant difference in the total incidence of complications and the incidence of different types of complications between the two groups (P > 0.05). One case of anastomotic flaccidity and two cases of intestinal obstruction in the open group were cured by surgery, and the other complications were improved after conservative treatment. There was no significant difference in the follow-up time between the two groups (P005). Five patients in the minimally invasive group were lost to follow-up, There was no significant difference in 5-year local recurrence rate, distant metastasis rate, overall survival rate and tumor-free survival rate between the two groups (P > 0.05). Conclusion: The prognosis of laparoscopic surgery for colonic tumors is similar to that of laparotomy, but the traumatic stress caused by surgery is small.

Keywords: Colon cancer; Laparotomy; Laparoscopic surgery; Radical surgery; Prognosis; Trauma; Stress response.