A STUDY OF CORD BLOOD LIPID PROFILE IN NEWBORNS OF ALL GESTATIONAL AGE DELIVERED IN AVMCH, PUDUCHERRY

Ajinkya Wazurkar*, A. Dharmalingam, N. S. Raghupathy

ABSTRACT

Background: Cardiovascular Diseases are major cause of death in India of which IHD and Stroke constitute major part. Foetal origins hypothesis was proposed by Barker which asserts that in utero stress can result in adaptations and programming in the initial critical period of life. It has been widely reported that hypercholesterolemia, a significant risk factor of cardiovascular disease, can be diagnosed at the time of birth by an elevated cholesterol level in umbilical cord blood. This study was done to compare the lipid Profile values between Preterm and Term newborns. Methods: This was a cross sectional study done on 100 newborns. The study was done in the Department of Paediatrics in AVMCH, Puducherry. Simple convenient sampling method was followed. Cord blood was taken after delivery and assessed for Total Cholesterol, Triglycerides, LDL and HDL levels. Babies were classified into Term (37-42 weeks) and preterm (<37 weeks). Gestational age was calculated by LMP, if not available 1st trimester USG and New Ballard scoring was used respectively. Results: In this cross sectional study Term and Preterm babies were 53 and 47 respectively. Lipid profile values were found to be statistically significant for all components between preterm and term babies, between two components that is Total Cholesterol and LDL between AGA and SGA babies whereas no significant difference found between male and female. Conclusion- Lipid profile values are elevated in Preterm and SGA babies whereas gender of baby do not influence lipid values.

Keywords: Cord blood, lipid profile, Total cholesterol, Triglycerides, LDL, HDL.