STUDY OF OBSTETRIC OUTCOME AND OPTIMUM MAGNESIUM SULPHATE DOSING SCHEDULE IN ECLAMPSIA PATIENTS AT A TERTIARY CARE HOSPITAL

Fasiha Tasneem*, Bhawna Parane and Vinutha M. Sharma

ABSTRACT

Background: Eclampsia is a common medical emergency of pregnancy mainly seen in 5% to 10% of all pregnancies. The objective of the present study was to find out the obstetric outcome of eclampsia patients and to find out the dosing schedule of magnesium Sulphate in eclampsia patients. Methods: All the cases of impending eclampsia and eclampsia getting admitted in tertiary care hospital are analysed prospectively for obstetric outcome and optimum magnesium sulphate dosing schedule over a study period of 18 months. Results: In this study of 248 patients, 114 of imminent eclampsia and 134 are of eclampsia. Incidence was higher in primigravida in the age group of 21-25 years. 62.1% delivered vaginally, 31.9% by caesarean delivery and 6% by instrumental delivery. All imminent eclampsia patients received 14 gm MgSO4 and in none of them convulsions occurred. In eclampsia patients, according to standard Pritchards regime, majority (38.8%) patients received 44 gm of MgSO4. Conclusion: To reduce the incidence and complication of eclampsia, there is a dire need to improve antenatal care at community level. MgSO4 as a drug of choice has stood the test of time for control of eclampsia and prevention of further convulsions. Even though various drugs and methods are tried, the definitive management for treatment of eclampsia is after control of convulsions and hypertension, delivery at tertiary care hospital. Termination should be individualized.

Keywords: Eclampsia, Hypertension, Convulsions, Magnesium Sulphate.