THE STUDY OF AN ADVERSE DRUG REACTION CAUSED BY FIRST LINE ANTI-TUBERCULAR DRUGS

Dr. Shaik Mohammed Sumeer* and Dr. Noorush Shifa Nizami

ABSTRACT

Development of drug resistance in the treatment of tuberculosis, especially multi-drug resistant TB (MDR-TB) had begunthe Global publichealth issue in many countries. Drug resistance maybe developeddue to infection with the resistant strain or it maybe a result of the insufficient treatment, usually when the patient is exposed to irregular drug supply, single drug, poor drug quality, selective drug intake or maybe the erraticabsorption of medications, which is usually rare. We present a case in which the patient is already diagnosed with ATT drugs and came to the hospital with the adverse effects of the ATT drugs and the patient was presented with the complaints of vomiting, loose stools, burning micturition and epigastric burning sensation sincetwo days and was diagnosed as drug – induced gastritis and was treated with antibiotics, proton pump inhibitors, acid blockers and the other supportive treatment was given.

Keywords: ADRs, Anti Tubercular treatment, Mycobacterium, DOTS Therapy.