EVALUATION OF ANTIDIABETIC ACTIVITY OF LEAVES OF AILANTHUS EXCELSA ON EXPERIMENTAL ANIMALS

Mohd Shahvez, Dr. Vrish Dhwaj Ashwlayan and Jiyaul Hak*

ABSTRACT

The current study is an effort to examine the effect of Ailanthus excelsa leaves extract on streptozotocin induced diabetes in Wistar rats. Two groups of streptozotocin induced diabetic rats were orally treated through Ailanthus excelsa leaves extract (150 and 300mg/kg) respectively. The blood glucose level, body mass, Glycosylated hemoglobin, liver glycogen, lipid profile, Antioxidant status were measured at the finish of the study that is after 40 days of treatment Ailanthus excelsa leaves extract were originate to be significant (p < 0.05) in dropping the blood glucose level, glycosylated hemoglobin, triglyceride, cholesterol, LDL, VLDL, HDL, blood urea, lipid profile, while both the treatments improved body weight, liver glycogen satisfied status once compared to the diabetic control. It have been concluded that Ailanthus excelsa leaves extract, in adding to the antidiabetic activity, too own antihyperlipidemic activities in the streptozotocininduced diabetic model.

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