ANTIBACTERIAL POTENTIAL AND PHYTOCHEMICAL ANALYSIS OF PIPER BETEL AND TINOSPORA CORDIFOLIA

*Pooja P. Mankar, Rameshwar V. Darade and Dr. Archana S. Pethe

ABSTRACT

The unimpeded use of antibiotics even over a small infections, progresses the development of superbugs and this started with one of the broad spectrum beta lactam antibiotics ampicillin many years ago. Small skin infections need to be treated with traditional Indian herbal therapy which will lead a better way to stop the emergence of antibiotic resistant bacteria. The present study focuses on the antibacterial effect of two herbal extracts of leaves of Piper betel and Tinospora cordifolia and their phytochemical analysis. The water and ethanol extracts of Piper betel and Tinospora cordifolia were prepared to assess the activity against pathogenic bacteria isolated from otitis externa. The broad spectrum antibiotic imipenem was taken as control. Both water and ethanolic extracts of Piper betel exhibited good activity against Klebsiella pneumoniae strain CIFRI-OBBKP2, Staphylococcus simiae CCM 7213, Bacillus subtilis strain NCDO 1769 and Acinetobacter pittii DSM 21653 strain ATCC 19004 as compared to Tinospora cordifolia.

Keywords: Piper betel, Tinospora cordifolia, Antimicrobial, Phytochemical.