EVALUATION OF VALERIANA WALLICHII ROOT EXTRACT FOR ANTI ULCER POTENTIAL IN EXPERIMENTAL ANIMAL

Sajid*, Dr. Anurag Chaudhary1 and Jiyaul Hak

ABSTRACT

The procedure for reducing ulcers by a wound caused by immersion in cold water, includes fasting animals 18-24 hours to the study. Wounds was formerly treated through interfuse individual animals in a closed cage and immersed into a water tank, (15 to 20°C) slowly but surely to a xiphoid level for 17 hours in the event of a “water-based model”, or 24 hours into water cold as soon as using a “solid cool water model” or holding a cold air freezer at a temp of 2 to 3 °C intended for 2 to 4 hours in the case of a “cold pressure model” Appropriate treatment (car (2 ml/kg), Ranitidine (50 mg/Kg), V. wallichii root extract (200 & 400 mg/Kg) given orally twice for seven days. The results of this study concluded, Hydroalcoholic extract (200 mg/kg) was less effective compared with various parameters such as ulcer index, pH, total and free acid compared to standard (Ranitidine 50 mg/kg).

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