OCIMUM SANCTUM THERAPEUTIC POTENTIAL AGENT AGAINST ORAL PATHOGENS E.FEACALIS AND S.MUTANS ORGANISMS

Prajapati D.*, Khan F.*, Acharya A.

ABSTRACT

In this current study we have found that Eugenol (1-hydroxy-2-methoxy-4-allylbenzene), the active constituents present in O. sanctum L. is largely responsible for the therapeutic potentials. The antibacterial activity combined with anti-inflammatory and analgesic activities of O. sanctum, could make it useful in inflammatory disorder resulting from microbial infection. Enterococcus faecalis (E. faecalis) is one of the most common species. Present in the mouth and vagina and Streptococcus mutans (S. mutans) is a facultatively anaerobic, gram-positive coccus (round bacterium) commonly found in the human oral cavity and is a significant contributor to tooth decay. It is reported in many literatures that O. sanctum L. extract has anti-cancer potential. due to the combinatorial effect of anti-proliferative, apoptotic and anti-migratory effect of the O. sanctum extracts.

Keywords: O. sanctum, microbial activity, pathogen, bacteria.