ASSESSMENT OF IMPACT OF VARIOUS INTRACANAL MEDICAMENTS ON FRACTURE RESISTANCE OF ENDODONTICALLY TREATED TEETH IN PDL SIMULATED SAMPLES - AN IN VITRO STUDY

*Dr. Shruti Sharma, Dr. Rana K. Varghese, Dr. Ganesh Ramlal Mesharam, Dr. Naveen Kumar Gupta, Dr. Anita Chandrakar and Dr. Chandrabhan Gendley

ABSTRACT

Background: Intracanal medicaments have long been used for disinfection purposes between the sessions of endodontic procedures. This study aims to assess the impact of various intracanal medicaments on the fracture resistance of endodontically treated teeth. Materials and Methods: A total of 200 single-rooted mandibular premolars which were extracted for periodontal reasons were collected for this in vitro study. All roots were randomly assigned to five study groups (40 roots in each group); Group 1: Calcium Hydroxide (CH), Group 2: Combined use of Calcium Hydroxide and Chlorhexidine 2%, Group 3: Triple Antibiotic Paste (TAP), Group 4: Simvastatin and Group 5: Control group without addition of any substances. All specimens in each group were incubated for 1 month (Subgroup A) and 2 months (Subgroup B). Then, medicaments were removed and filled with gutta‑percha and AH26 sealer. All samples were tested for fracture resistance. One way ANOVA, Tukey post hoc test and Paired t test were used for the comparison between the groups. Results: Calcium Hydroxide and Calcium Hydroxide with Chlorhexidine increased the fracture resistance in a 1 month period and Simvastatin increased the fracture resistance after 2 months. Conclusion: No negative impact is observed with the medicaments, Calcium Hydroxide, Calcium Hydroxide + Chlorhexidine, Triple Antibiotic Paste and Simvastatin on the fracture resistance of endodontically treated teeth.

Keywords: Calcium Hydroxide, Chlorhexidine, Triple Antibiotic Paste, Simvastatin, root canal therapy.