REVIEW: COMPREHENSIVE STUDY OF DRUGS USED IN COVID 19 AND THEIR MODES OF ACTION

Atul Dilip Muthal*, Nilam Subhash Patangare, Divya Goraksha Thite, Rashmi Ramesh Pawar

ABSTRACT

The focus of the review is that Hydroxychloroquine is the drug primarily used to treat the covid virus. Acute Respiratory distress syndrome is a severe form of acute respiratory distress corona virus is a new and quickly spreading virus that causes corona virus illness. In 2019, Hydroxychloroquine and Chloroquine were both used against COVID-19. Favipiravir has a large margin of efficacy against various single-stranded RNA viruses, is well tolerated in humans, and has a strong barrier to resistance, depending on its mode of action and safety. Remdesivir is an analog of nucleotide prodrug that mainly inhibits SARS-CoV-2 RdRp. Its viral activities against SARS-CoV-2 have been shown both in vivo and vitro studies and are the most promisingly used till date due to its antiviral nature.

Keywords: Corona virus, Hydroxychloroquine, Favipiravir, Remdesvir, Mechanism.