CURCUMINOIDS: REVIEW OF THERAPEUTIC POTENTIALS

Deepak Yadav*, Dr. Jaya Agnihotri and Dr. Indira Parab

ABSTRACT

Curcumin has long been recognized for its medicinal properties and it has received interest from both the medical and scientific world and from culinary enthusiasts, as it is the major source of the polyphenols curcumin. curcumin helps in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, hyperlipidemia and anxiety . It help in the management of exercise-induced inflammation and muscle soreness, thus it enhances recovery and performance in active people. In addition, a relatively low dose of the complex will provide the health benefits for people that do not have diagnosed health conditions. These benefits can be attributed to its antioxidant as well as anti-inflammatory effects as well . Ingesting the curcumin by itself does not lead to the associated with health benefits due to its poor absorption and bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. There are several components that will increase bioavailability. The aim of this review was to overview the biological activities of curcuminoids and other biomolecules from turmeric and also discussed the effects and various applications of curcuminoids.

Keywords: CUR - Curcumin DCM - Dichloromethane DMC - Demethoxy curcumin BDMC - Bisdemethoxycurcumin BDNF- Brain-derived neurotrophic factor