A REVIEW ON PHARMACOLOGICAL AND SYNTHETIC METHODS OF BENZIMIDAZOLE NUCLEUS

Sanjay Singh*, Gaurav Kumar, Manisha Negi and Salman

ABSTRACT

Benzimidazole is an organic compound which consists of benzene ring fused with imidazole heterocyclic ring and shows aromaticity. Benzimidazole moiety has been showed more potent role in the field of research. It is an amphiprotic compound, its pseudo acidic in character and alkali molecule is show planner properties. Reported moiety is a constituent of Vitamin B12. Benzimidazoles are regarded as a promising types of bioactive heterocyclic moiety that showed a various types of biological activity like antibacterial, antiviral, analgesic, antitubercular, anti HIV, anticonvulsant, anti proliferative, anti inflammatory, anti-helmintics, antioxidant, anti neoplastic, proton pump inhibitor and antihypertensive. In this review article has been discussed about introduction, preparation, physical properties, chemical properties and uses.

Keywords: Benzimidazole, FT-NMR, FT-IR and UV.