EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

ANTI-HYPERTENSIVE ACTIVITY OF SIDDHA HERBO- MINERAL FORMULATION ELADHI CHOORANAM IN SPONTANEOUSLY HYPERTENSIVE RATS

Tamilselvan R.*, Bharathi K., Semalatha S.

ABSTRACT

Siddha drugs are currently very popular among the people. At the same time there has been an increase in the research of scientific siddha drugs. The reason is that it acts on diseases and cures them and causes fewer side effects. One of the secure and sinful anti-hypertensive Siddha medicine is Eladhi Chooranam (ECM). Which is used for this study to identify the anti- Hypertensive activity by using spontaneously hypertensive rats (SHR). Systolic blood pressure (SBP) and heart rate measurement of SH rats was carried out using tail-cuff method plethysmography (LE 5001 Pressure Meter). The SH rats were randomly divided in to four groups and each consists of six rats per group. All the groups were categorized into control, group received verapamil hydrochloride 12.5mg control, ECM 200mg and ECM 400mg. Test drug Eladhi chooranam was administrated (200mg/400mg/kg) orally. The systolic blood pressure (SBP) and heart rate (HR) of the rats were recorded. Administration of ECM for 28 days remarkably reduced the SBP and HR. The tidings obtained from this study shows decrease in Systolic BP and Heart Rate was more conclusive high dose level 400mg/kg than low dose 200mg/kg indicated bravery response to anti-hypertensive activity of the Siddha formulation Eladhi chooranam in a research-based way.

Keywords: Eladhi chooranam, Siddha, Anti-hypertensive, Spontaneously Hypertensive rat.

[Full Text Article] [Download Certificate]