A BRIEF REVIEW ON MUCOADHESIVE DRUG DELIVERY SYSTEM IN PHARMACOLOGICAL TECHNOLOGY

*Utsav S. Patel, A. R. Dhankani, Mansi Amitkumar Dhankani, Dr. Dhaval K. Patel and Dr. S. P. Pawar

ABSTRACT

Since 1980 the concept of mucoadhesion has gained considerable interest in pharmaceutical technology. Mucoadhesion describe the attractive forces between a biological material and mucus membrane. Mucoadhesion drug delivery system prolong the resident time and facilitate in contact of the dosage form with the underlined absorption surface which results in improvements of the therapeutic performance of the drug. The mechanism of the mucoadhesive contain context stage and consideration stage which can be explained in diffusion and dehydration theory. Mucoadhesive theory include wetting theory, diffusion theory, fracture theory and electronic theory. Mucoadhesive dosage form an available in tablets patches, gels and solutions in dosage form. The mucoadhesive drug delivery system depends selection of suitable polymer with excellent mucosal adhesive properties. The review aims at compiling to potential benefits of mucoadhesive drug delivery system.

Keywords: Mucoadhesive, Drug delivery, Polymers.