CLINICOPATHOLOGICAL PROFILE OF LUNG CANCER IN A TERTIARY CARE HOSPITAL IN DEPARTMENT OF RADIOTHERAPY IN NORTH INDIA

Dr. Hanifa Akhtar, Dr. Subiya Kaneez, *Dr. Amat-us-Sami, Dr. Ashfaq Hafiz and Dr. Sajad Ahmad Dar

ABSTRACT

Introduction: Among malignant diseases, lung carcinoma is the most common cancer in men worldwide in terms of both incidence and mortality. Its increasing incidence in developing countries like India is an important public health problem. This work aimed to study the demographic, clinical, radiological, and histological features of patients with confirmed lung cancer. Materials and Methods: A total of 100 patients with histologically confirmed lung cancer at a tertiary care center in North India from December 2019 to November 2021 were studied and analyzed. Results: Out of 100 diagnosed lung cancer patients, 82% were men and 18% women; 65% of patients were aged more than 60 years. Majority were smokers (81%) and all were men. Cough (90%) was the most common presenting symptom followed by dyspnea (67%), chest pain (46%), and hemoptysis (35%). Of the 100 patients, 54(54%) had soft tissue density mass lesion on radiograph. Squamous cell carcinoma (SCC) was the diagnosed histological cell type in 46 (46%) patients and adenocarcinoma in 42 (42%) patients. Distant metastasis was observed in 42 (42%) patients. Conclusion: In this study, the most common histopathological cell type is SCC. Patients aged more than 50 years and smokers are at high risk of lung cancer. Patients with a smoking history and persistent respiratory symptoms should be promptly evaluated for lung malignancy.

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