EVALUATION OF ANTHALMATIC ACTIVITY OF PHYLLANTHUS AMARUS LEAVES EXTRACT IN EARTHWORMS (PHERETIMA POSTHUMA)

Divya G. Thite*, Yojana A. Kunjir, Tejal B. Korde, Pragti S. Dukare, Abhilasha T. Temgire and Priyanka R. Khemnar

ABSTRACT

In this paper, the anthelmintic activity of Evaluation Of Anthalmatic Activity Of phyllanthus amarus Extract In Earthworms (Pheretima Posthuma) leaves extract is evaluated. Albendazole, methanol, chloroform and water were used during experimental protocol. Extraction of plant leaves was carried out by using Soxhlet apparatus and aqueous extraction is done by using maceration technique. The anthelmintic activity was evaluated using Indian adult Earthworms (Pheretima posthuma). The result obtained from experimental data, showed significant anthelmintic activity against Earthworms. Screening of plant extract was performed for complete death and paralysis of worms. The result shows a dose dependent increase in activity of the extract at 5, 10 and 20 mg/ml concentration. Results were comparable along the standard drug albendazole, which indicates that the phyllanthus amarus leaf shows the potent anthelmintic activity and has good action on worms, as compared with standard drug.

Keywords: Anthelmintic activity, phyllanthus amarus, Pheretima posthuma, albendazole.