EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

THE ROLE OF RADIOTHERAPY IN SPINAL CORD COMPRESSION CAUSED BY SOLITARY BONE PLASMACYTOMA: A CASE REPORT

Mohamed Saadoune*, Raouah Mehdi, Honorine Imfurankunda Habimana and Sacino Florence

ABSTRACT

Introduction: Solitary bone plasmacytoma (SBP) is a hematopoietic malignancy occurring in bone tissue, which often causes bone destruction at the site of the lesion. When the lesion occurs in the spine and causes spinal stenosis and compression of the spinal cord, surgery is performed as an adjuvant treatment before radiotherapy. Case Presentation: A 56-year-old patient suffered of back pain followed by muscular weakness of the lower limbs. manipulation by an osteopath with the appearance 48 hours later of a difficulty to walk, motor deficit with motor testing at 0/5 in the lower limbs for 1 week with ROT +/+ in patellar present not sharp, not polykinetic with Babinski indifferent to both feet,CT and MRI examination of the spinal after emergency admission revealed T8 vertebral pathological fracture with associated spinal stenosis and spinal cord compression. PET-CT indicated a hypermetabolic soft tissue mass in the T8 vertebral body. Finally, a needle biopsy was performed at the lesion site and a diagnosis of SBP was made. Radiotherapy was immediately followed and the spinal cord compression was relieved a month later. Conclusion : For patients with SPB resulting in pathological fracture of the thoracic vertebra with spinal stenosis and compression of the spinal cord, forgoing surgery and undergoing radiation therapy alone may be an option.

Keywords: Solitary plasmocytomas, Spinal cord compression, paraplegia, radiotherapy.


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