SELECTIVE WILD MEDICINAL PLANTS IN MADINAH CITY AGAINST PATHOGENIC BACTERIA

*Moayad S. Waznah and Sultan M. Alsharif

ABSTRACT

Background: Bacterial resistant to antibiotic needs an alternatives agent due to huge uses globally. Wild plant extraction is considered a source to solve the problem. The aim of this study is evaluating and comparing the effectiveness of five wild plants extracted by ethanol on the selected pathogenic bacterial strains Escherichia coli (E. coli) and Bacillus cereus (B. cereus) as Gram-negative bacteria, Streptococcus pneumoniae (S. pneumoniae) and Staphylococcus aureus (S. aureus) as Gram-positive bacterium. Methods: Experiments achieved with five wild plants collected from Madinah, Ferula asafetida (F. asafetida), Xanthium strumarium (X. strumarium), Onopordum heteracanthum (O. heteracanthum) and Glinus lotoides (G. lotoides). All were in vitro and alcoholic plant extracts concentrations (100, 50, 25 mg / ml) prepared before antibacterial sensitivity accomplished using disc diffusion methods. Pathogens used in this study were E. coli, B. cereus, S. pneumoniae and S. aureus. Results: Several plant extracts showed inhibition zones in Petri dishes. The data demonstrated that Ferula asafetida affects all bacterial strains. On contrary, Ficus cordata and Ficus cordata showed the lowest effect. Conclusion: Among the studied plants, Ferula asafetida showed the highest potentially and efficiency as natural antibacterial agent, and thus could be a promising medicinal plant against bacteria.

Keywords: Gram-negative bacteria, Gram-positive bacteria, Antibiotic resistance, antibacterial, plant extract, Madinah, wild plants.